Best Peptides for Immune Support
Peptides that modulate immune function, enhance immune response, and support overall immune health.
Top Peptides for Immune Support
| Peptide | Evidence | Use Case | Actions |
|---|---|---|---|
| ThymulinTop Choice Thymulin (Facteur Thymique Sérique) is a zinc-dependent nonapeptide hormone produced by thymic epithelial cells. It plays important roles in T-cell differentiation and immune system maturation. | medium | Thymic hormone supporting T-cell function | |
| VIP (Vasoactive Intestinal Peptide)Top Choice VIP is a 28-amino acid neuropeptide with wide-ranging effects throughout the body. It acts as a neurotransmitter, neuromodulator, and immune regulator with particular importance in gut and lung function. | medium | Potent immunomodulatory effects, used in chronic inflammatory conditions | |
| Alpha-DefensinTop Choice Alpha-defensins are small cationic peptides that are key components of the innate immune system. They have broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses. | high | Key innate immune peptide with broad antimicrobial activity | |
| LactoferricinTop Choice Lactoferricin is an antimicrobial peptide derived from lactoferrin, a protein found in milk and other secretions. It has potent antibacterial, antiviral, and antifungal properties. | high | Potent natural antimicrobial peptide from lactoferrin | |
| Thymosin Alpha-1Top Choice Thymosin Alpha-1 is a peptide naturally produced by the thymus gland that plays a crucial role in immune system modulation. It is approved in over 35 countries for various conditions including hepatitis B and C. | high | Primary use case - extensive clinical evidence for immune modulation | |
| LL-37 (Cathelicidin)Top Choice LL-37 is the only human cathelicidin antimicrobial peptide. It plays crucial roles in innate immunity and has shown diverse biological activities including antimicrobial, immunomodulatory, and wound healing properties. | high | Primary antimicrobial and immunomodulatory peptide | |
| ThymalinTop Choice Thymalin is a polypeptide preparation derived from calf thymus. Developed in Russia, it has been used for decades to support immune function and has shown potential anti-aging effects in long-term studies. | high | Decades of clinical use for immune modulation in Eastern Europe | |
| Semax Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone). Developed in Russia as a nootropic and neuroprotective agent. | low | Some evidence for immunomodulatory effects | |
| NA-Selank Amidate NA-Selank Amidate (N-Acetyl Selank Amidate) is an enhanced version of Selank with improved stability and blood-brain barrier penetration. The modifications increase bioavailability and duration of cognitive and anxiolytic effects. | low | Retains immunomodulatory properties of parent compound | |
| Selank Selank is a synthetic peptide derived from the naturally occurring immunomodulatory peptide tuftsin. Developed in Russia for anxiety and cognitive enhancement. | medium | Derived from tuftsin, has immunomodulatory properties |