VIP (Vasoactive Intestinal Peptide)
VIP is a 28-amino acid neuropeptide with wide-ranging effects throughout the body. It acts as a neurotransmitter, neuromodulator, and immune regulator with particular importance in gut and lung function.
Mechanism of Action
Binds to VPAC1 and VPAC2 receptors to modulate immune responses, regulate circadian rhythms, promote vasodilation, and support barrier function in gut and lungs. Has potent anti-inflammatory effects.
Dosage Overview
Dose Range
100 mcg – 200 mcg
Route
intranasal
Frequency
1x daily
Cycle Length
2–8 weeks
Reconstitution
Typical Dosage (Research)
Intranasal: 50-200mcg 1-3 times daily for chronic inflammatory conditions. Some protocols use subcutaneous administration. Dosing varies by condition.
Intranasal is most common for inflammatory conditions. Subcutaneous injection also used. Must be stored cold and protected from light.
Considerations for Men & Women
Women: Vasoactive intestinal peptide plays roles in reproductive biology — present in uterine and ovarian tissue. Intranasal VIP research focuses on anti-inflammatory effects. May affect prolactin levels. Avoid exogenous use during pregnancy.
Men: Same anti-inflammatory and vasodilatory research interest. VIP plays a role in erectile function and spermatogenesis. Intranasal delivery for systemic effects.
Individual responses vary. These notes reflect general trends from research literature and are not medical advice.
Quick Calculator
Quick Calculator
Concentration: 2,500 mcg/ml
Volume to inject: 0.04 ml
Syringe units (U-100): 4.0 units
Pre-filled with VIP (Vasoactive Intestinal Peptide) defaults. Adjust values as needed.
Side Effects & Risks
May cause nasal irritation, flushing, headache, or temporary diarrhea. Generally well-tolerated at standard doses.
May affect blood pressure due to vasodilatory effects. Limited human research for many applications. Quality and stability concerns.
Who Uses VIP (Vasoactive Intestinal Peptide)
Those with chronic inflammatory conditions (CIRS/mold illness), gut dysfunction, individuals seeking immune modulation.
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