Best Peptides for Gut Health
Peptides that support gut lining integrity, digestive function, and gastrointestinal healing.
Top Peptides for Gut Health
| Peptide | Evidence | Use Case | Actions |
|---|---|---|---|
| BPC-157Top Choice Body Protection Compound-157 is a synthetic peptide derived from a protein found in human gastric juice. It has shown remarkable healing properties in research studies. | high | Gastric pentadecapeptide with strong evidence for gut healing | |
| KPVTop Choice KPV is a tripeptide (Lys-Pro-Val) derived from alpha-melanocyte-stimulating hormone (α-MSH). It retains the potent anti-inflammatory properties of the parent hormone without the tanning or other melanocortin effects. | medium | Potent anti-inflammatory effects beneficial for gut conditions | |
| VIP (Vasoactive Intestinal Peptide)Top Choice VIP is a 28-amino acid neuropeptide with wide-ranging effects throughout the body. It acts as a neurotransmitter, neuromodulator, and immune regulator with particular importance in gut and lung function. | medium | Supports gut barrier function and reduces intestinal inflammation | |
| Semaglutide Semaglutide is a GLP-1 receptor agonist that has revolutionized weight management and diabetes treatment. FDA-approved as Ozempic (diabetes), Wegovy (weight loss), and Rybelsus (oral form), it has become one of the most prescribed peptides worldwide. | medium | Slows gastric emptying and affects gut-brain signaling | |
| Lactoferricin Lactoferricin is an antimicrobial peptide derived from lactoferrin, a protein found in milk and other secretions. It has potent antibacterial, antiviral, and antifungal properties. | medium | Supports gut barrier and microbiome through antimicrobial activity | |
| Octreotide Octreotide (Sandostatin) is a synthetic somatostatin analog FDA-approved for acromegaly, carcinoid tumors, and VIPomas. It inhibits growth hormone and various GI hormones. | high | Controls GI hormone hypersecretion in specific conditions |
Body Protection Compound-157 is a synthetic peptide derived from a protein found in human gastric juice. It has shown remarkable healing properties in research studies.
Gastric pentadecapeptide with strong evidence for gut healing
KPV is a tripeptide (Lys-Pro-Val) derived from alpha-melanocyte-stimulating hormone (α-MSH). It retains the potent anti-inflammatory properties of the parent hormone without the tanning or other melanocortin effects.
Potent anti-inflammatory effects beneficial for gut conditions
VIP is a 28-amino acid neuropeptide with wide-ranging effects throughout the body. It acts as a neurotransmitter, neuromodulator, and immune regulator with particular importance in gut and lung function.
Supports gut barrier function and reduces intestinal inflammation
Semaglutide is a GLP-1 receptor agonist that has revolutionized weight management and diabetes treatment. FDA-approved as Ozempic (diabetes), Wegovy (weight loss), and Rybelsus (oral form), it has become one of the most prescribed peptides worldwide.
Slows gastric emptying and affects gut-brain signaling
Lactoferricin is an antimicrobial peptide derived from lactoferrin, a protein found in milk and other secretions. It has potent antibacterial, antiviral, and antifungal properties.
Supports gut barrier and microbiome through antimicrobial activity
Octreotide (Sandostatin) is a synthetic somatostatin analog FDA-approved for acromegaly, carcinoid tumors, and VIPomas. It inhibits growth hormone and various GI hormones.
Controls GI hormone hypersecretion in specific conditions