Alpha-Defensin

Alpha-defensins are small cationic peptides that are key components of the innate immune system. They have broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses.

Mechanism of Action

Insert into microbial membranes to form pores, leading to cell death. Also have immunomodulatory effects including chemotaxis of immune cells and cytokine modulation.

Typical Dosage (Research)

Research compound - dosing varies by application. Typically studied in laboratory and early clinical research settings rather than for general use.

Various routes studied including topical, local injection, and systemic administration depending on application.

Side Effects & Risks

Limited human use data. May cause local inflammation. Potential for immune activation effects.

Primarily research compound. Broad immunomodulatory effects may have unintended consequences. Not available for general use.

Who Uses Alpha-Defensin

Researchers studying innate immunity, those in clinical trials for infectious disease or wound healing applications.