Leuphasyl

Leuphasyl (Pentapeptide-18) is a cosmetic peptide that reduces muscle tension through a mechanism similar to enkephalins. Often combined with Syn-Ake for enhanced anti-wrinkle effects.

Mechanism of Action

Mimics enkephalin and binds to enkephalin receptors on muscle cells, reducing acetylcholine release and thereby decreasing muscle contraction intensity.

Typical Dosage (Research)

Topical: 3-8% concentration in serums. Often used in combination products with other muscle-relaxing peptides.

Topical application to expression lines. Best results with consistent twice-daily use over 8+ weeks.

Side Effects & Risks

Very well-tolerated topically. No significant adverse effects reported at cosmetic concentrations.

Results are subtle compared to injectable treatments. Requires consistent long-term use for visible effects.

Who Uses Leuphasyl

Those building comprehensive anti-wrinkle skincare routines, individuals seeking to complement other cosmetic peptides.