Leuphasyl
Leuphasyl (Pentapeptide-18) is a cosmetic peptide that reduces muscle tension through a mechanism similar to enkephalins. Often combined with Syn-Ake for enhanced anti-wrinkle effects.
Mechanism of Action
Mimics enkephalin and binds to enkephalin receptors on muscle cells, reducing acetylcholine release and thereby decreasing muscle contraction intensity.
Dosage Overview
Dose Range
200 mcg – 500 mcg
Route
topical
Frequency
2x daily
Cycle Length
4–8 weeks
Reconstitution
Typical Dosage (Research)
Topical: 3-8% concentration in serums. Often used in combination products with other muscle-relaxing peptides.
Topical application to expression lines. Best results with consistent twice-daily use over 8+ weeks.
Considerations for Men & Women
Women: Pentapeptide that works synergistically with SNAP-8 to reduce expression lines. Topical cosmetic use only. No systemic or hormonal effects.
Men: Same anti-wrinkle benefits. Topical application. No sex-specific considerations.
Individual responses vary. These notes reflect general trends from research literature and are not medical advice.
Quick Calculator
Quick Calculator
Concentration: 2,000 mcg/ml
Volume to inject: 0.10 ml
Syringe units (U-100): 10.0 units
Pre-filled with Leuphasyl defaults. Adjust values as needed.
Side Effects & Risks
Very well-tolerated topically. No significant adverse effects reported at cosmetic concentrations.
Results are subtle compared to injectable treatments. Requires consistent long-term use for visible effects.
Who Uses Leuphasyl
Those building comprehensive anti-wrinkle skincare routines, individuals seeking to complement other cosmetic peptides.
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