Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-1 (Pal-GHK) is a lipopeptide that stimulates collagen production. It's one of two peptides in the Matrixyl 3000 complex, working synergistically with Palmitoyl Tetrapeptide-7.
Mechanism of Action
Mimics the skin's own mechanism for producing collagen by acting as a messenger peptide that signals fibroblasts to produce more collagen and other extracellular matrix components.
Dosage Overview
Dose Range
500 mcg – 2 mg
Route
topical
Frequency
2x daily
Cycle Length
4–12 weeks
Reconstitution
Typical Dosage (Research)
Topical: Typically 2-4% in serums, often combined with Palmitoyl Tetrapeptide-7 as Matrixyl 3000.
Topical application 1-2 times daily. The palmitoyl group enhances skin penetration compared to non-lipidated versions.
Considerations for Men & Women
Women: Collagen-stimulating peptide used topically. Works synergistically with palmitoyl tetrapeptide-7. No systemic effects or hormonal interactions.
Men: Same collagen stimulation. Topical use only. No sex-specific differences.
Individual responses vary. These notes reflect general trends from research literature and are not medical advice.
Quick Calculator
Quick Calculator
Concentration: 2,500 mcg/ml
Volume to inject: 0.20 ml
Syringe units (U-100): 20.0 units
Pre-filled with Palmitoyl Tripeptide-1 defaults. Adjust values as needed.
Side Effects & Risks
Very well-tolerated. Suitable for most skin types including sensitive skin.
Results take 8-12 weeks of consistent use. Efficacy varies between individuals.
Who Uses Palmitoyl Tripeptide-1
Those seeking collagen stimulation, anti-aging skincare users, individuals with mature or sun-damaged skin.
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