Hexarelin

Hexarelin is a potent synthetic hexapeptide growth hormone secretagogue. It provides the strongest GH release among GHRPs but is associated with rapid desensitization of receptors.

Mechanism of Action

Acts as a ghrelin mimetic with high potency at the GHS receptor. Provides powerful GH release but receptor desensitization occurs faster than with other GHRPs, requiring cycling.

Typical Dosage (Research)

Typical dosing: 100-200mcg administered 2-3 times daily for 4-6 weeks, followed by an equal off period to allow receptor resensitization.

Subcutaneous injection. Cycling is essential to maintain effectiveness. Often used in short bursts rather than continuous protocols.

Side Effects & Risks

Water retention, cortisol and prolactin increase, hunger (moderate), tingling, and potential blood pressure effects.

Rapid receptor desensitization limits long-term use. May have cardiac effects at high doses. Significant prolactin elevation possible.

Who Uses Hexarelin

Experienced peptide users seeking maximum GH release, those who can adhere to cycling protocols, bodybuilders during intensive phases.