Hexarelin
Hexarelin is a potent synthetic hexapeptide growth hormone secretagogue. It provides the strongest GH release among GHRPs but is associated with rapid desensitization of receptors.
Mechanism of Action
Acts as a ghrelin mimetic with high potency at the GHS receptor. Provides powerful GH release but receptor desensitization occurs faster than with other GHRPs, requiring cycling.
Dosage Overview
Dose Range
100 mcg – 300 mcg
Route
subcutaneous
Frequency
2x daily
Cycle Length
8–12 weeks
Reconstitution
Typical Dosage (Research)
Typical dosing: 100-200mcg administered 2-3 times daily for 4-6 weeks, followed by an equal off period to allow receptor resensitization.
Subcutaneous injection. Cycling is essential to maintain effectiveness. Often used in short bursts rather than continuous protocols.
Considerations for Men & Women
Women: Most potent GHRP — significant GH release but also notable cortisol and prolactin elevation. Prolactin increase is more relevant for women due to potential menstrual cycle effects. Desensitization occurs faster than other GHRPs; cycle accordingly.
Men: Potent GH release but rapid receptor desensitization limits long-term use. Cortisol and prolactin spikes should be monitored. Typically used in short bursts rather than continuous protocols.
Individual responses vary. These notes reflect general trends from research literature and are not medical advice.
Quick Calculator
Quick Calculator
Concentration: 2,500 mcg/ml
Volume to inject: 0.04 ml
Syringe units (U-100): 4.0 units
Pre-filled with Hexarelin defaults. Adjust values as needed.
Side Effects & Risks
Water retention, cortisol and prolactin increase, hunger (moderate), tingling, and potential blood pressure effects.
Rapid receptor desensitization limits long-term use. May have cardiac effects at high doses. Significant prolactin elevation possible.
Who Uses Hexarelin
Experienced peptide users seeking maximum GH release, those who can adhere to cycling protocols, bodybuilders during intensive phases.
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