PEG-MGF
PEG-MGF (PEGylated Mechano Growth Factor) is a variant of IGF-1 that is produced in response to muscle damage. PEGylation extends its half-life from minutes to several hours, making it practical for use.
Mechanism of Action
Activates muscle satellite cells (stem cells) and promotes their fusion to existing muscle fibers for repair and growth. MGF is produced naturally in response to mechanical stress on muscles.
Dosage Overview
Dose Range
400 mcg – 1.2 mg
Route
subcutaneous
Frequency
Weekly
Cycle Length
4–6 weeks
Reconstitution
Typical Dosage (Research)
Research protocols typically use 200-400mcg injected into targeted muscle groups 2-3 times weekly, usually post-workout.
Intramuscular injection, ideally into muscles trained that day. Best administered post-workout when satellite cell activation is relevant.
Considerations for Men & Women
Women: Limited research in women specifically. As a growth factor, standard pregnancy/breastfeeding contraindications apply. No established sex-specific differences in muscle repair signaling.
Men: Typically used post-exercise for localized muscle repair signaling. Injectable at the site of desired effect. No sex-specific dose adjustments established.
Individual responses vary. These notes reflect general trends from research literature and are not medical advice.
Quick Calculator
Quick Calculator
Concentration: 1,000 mcg/ml
Volume to inject: 0.40 ml
Syringe units (U-100): 40.0 units
Pre-filled with PEG-MGF defaults. Adjust values as needed.
Side Effects & Risks
Injection site soreness, potential hypoglycemia, and localized swelling. Generally well-tolerated.
Limited human research. May promote unwanted tissue growth. Quality and purity concerns with research products.
Who Uses PEG-MGF
Bodybuilders, athletes recovering from muscle injuries, those seeking targeted muscle development.
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MGF (Mechano Growth Factor) is a splice variant of IGF-1 that is produced locally in muscle tissue in response to mechanical stress. The non-PEGylated form has a very short half-life.