MGF (Mechano Growth Factor)

MGF (Mechano Growth Factor) is a splice variant of IGF-1 that is produced locally in muscle tissue in response to mechanical stress. The non-PEGylated form has a very short half-life.

Mechanism of Action

Activates muscle satellite cells (stem cells) and promotes their proliferation without differentiation, priming them for fusion with existing muscle fibers during repair and growth.

Typical Dosage (Research)

Due to extremely short half-life (minutes), typical protocols use 100-200mcg injected directly into target muscles immediately post-workout.

Intramuscular injection into trained muscles within minutes of workout completion. Must be used immediately after reconstitution due to instability.

Side Effects & Risks

Injection site soreness, potential hypoglycemia, localized swelling. Short half-life limits systemic effects.

Very short half-life makes practical use difficult. Limited research data. PEG-MGF version preferred for practicality.

Who Uses MGF (Mechano Growth Factor)

Researchers, advanced users seeking localized muscle effects, those who can inject immediately post-workout.