FGL
FGL (FG Loop) is a synthetic peptide that mimics the neural cell adhesion molecule (NCAM) FG loop region. It promotes neuroplasticity and has shown cognitive-enhancing effects in research.
Mechanism of Action
Binds to FGFR1 (fibroblast growth factor receptor 1) to activate downstream signaling cascades that promote neurite outgrowth, synaptic plasticity, and neuronal survival.
Dosage Overview
Dose Range
500 mcg – 1 mg
Route
intranasal
Frequency
1x daily
Cycle Length
4–8 weeks
Reconstitution
Typical Dosage (Research)
Research protocols have used subcutaneous doses ranging from 1-10mg. Intranasal administration also studied. Optimal dosing not established.
Subcutaneous injection or intranasal administration. Research compound with limited human dosing data.
Considerations for Men & Women
Women: NCAM-derived peptide for neural plasticity. Very limited human data. No established sex-specific differences. Standard precautions during pregnancy due to neurotrophic activity.
Men: Same research protocols apply. Intranasal delivery. Limited clinical data overall.
Individual responses vary. These notes reflect general trends from research literature and are not medical advice.
Quick Calculator
Concentration: 2.5 mg/ml
Volume to inject: 0.20 ml
Syringe units (U-100): 20.0 units
Pre-filled with FGL defaults. Adjust values as needed.
Side Effects & Risks
Limited human data available. Animal studies show good tolerability.
Very limited human research. Long-term effects unknown. Primarily studied in animal models.
Who Uses FGL
Researchers, advanced nootropic users, those interested in NCAM-based neuroplasticity enhancement.
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