FGL

FGL (FG Loop) is a synthetic peptide that mimics the neural cell adhesion molecule (NCAM) FG loop region. It promotes neuroplasticity and has shown cognitive-enhancing effects in research.

Mechanism of Action

Binds to FGFR1 (fibroblast growth factor receptor 1) to activate downstream signaling cascades that promote neurite outgrowth, synaptic plasticity, and neuronal survival.

Typical Dosage (Research)

Research protocols have used subcutaneous doses ranging from 1-10mg. Intranasal administration also studied. Optimal dosing not established.

Subcutaneous injection or intranasal administration. Research compound with limited human dosing data.

Side Effects & Risks

Limited human data available. Animal studies show good tolerability.

Very limited human research. Long-term effects unknown. Primarily studied in animal models.

Who Uses FGL

Researchers, advanced nootropic users, those interested in NCAM-based neuroplasticity enhancement.