SNAP-8

SNAP-8 (Acetyl Octapeptide-3) is a cosmetic peptide that reduces the appearance of wrinkles by modulating muscle contraction. It is often called 'topical Botox' though it works through a different mechanism.

Mechanism of Action

Mimics the N-terminal end of SNAP-25, competing with native SNAP-25 for position in the SNARE complex. This reduces neurotransmitter release at the neuromuscular junction, decreasing muscle contraction.

Typical Dosage (Research)

Topical: 3-10% concentration in serums or creams, applied 1-2 times daily to target areas (forehead, crow's feet, etc.).

Topical application only. Should be applied to clean skin. Often formulated with penetration enhancers for better absorption.

Side Effects & Risks

Generally well-tolerated topically. Rare reports of mild skin irritation. No systemic effects at cosmetic doses.

Effects are temporary and subtle compared to injectable neurotoxins. Quality and concentration vary widely between products.

Who Uses SNAP-8

Those seeking non-invasive wrinkle reduction, individuals looking to extend time between Botox treatments.