VIP (Vasoactive Intestinal Peptide) vs Adamax

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

VIP (Vasoactive Intestinal Peptide)

VIP is a 28-amino acid neuropeptide with wide-ranging effects throughout the body. It acts as a neurotransmitter, neuromodulator, and immune regulator with particular importance in gut and lung function.

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Adamax

Adamax is a modified version of Semax with an adamantane group attached, designed to enhance its nootropic effects and extend duration of action compared to standard Semax.

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Side-by-Side Comparison

AspectVIP (Vasoactive Intestinal Peptide)Adamax
MechanismBinds to VPAC1 and VPAC2 receptors to modulate immune responses, regulate circadian rhythms, promote vasodilation, and support barrier function in gut and lungs. Has potent anti-inflammatory effects.Similar to Semax - enhances BDNF expression and modulates dopamine/serotonin systems. The adamantane modification may increase lipophilicity and CNS penetration.
Typical DosageIntranasal: 50-200mcg 1-3 times daily for chronic inflammatory conditions. Some protocols use subcutaneous administration. Dosing varies by condition.Intranasal: 100-500mcg 1-2 times daily. Lower doses than standard Semax may be effective due to enhanced potency.
AdministrationIntranasal is most common for inflammatory conditions. Subcutaneous injection also used. Must be stored cold and protected from light.Intranasal spray is most common route. More stable than standard Semax. Often used for acute cognitive enhancement.
Side EffectsMay cause nasal irritation, flushing, headache, or temporary diarrhea. Generally well-tolerated at standard doses.Similar to Semax - possible irritability, hair shedding, or overstimulation. May have stronger effects than standard Semax.
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Key Differences

Unique to VIP (Vasoactive Intestinal Peptide):

Unique to Adamax:

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