PEG-MGF vs Lactoferricin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

PEG-MGF

PEG-MGF (PEGylated Mechano Growth Factor) is a variant of IGF-1 that is produced in response to muscle damage. PEGylation extends its half-life from minutes to several hours, making it practical for use.

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Lactoferricin

Lactoferricin is an antimicrobial peptide derived from lactoferrin, a protein found in milk and other secretions. It has potent antibacterial, antiviral, and antifungal properties.

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Side-by-Side Comparison

AspectPEG-MGFLactoferricin
MechanismActivates muscle satellite cells (stem cells) and promotes their fusion to existing muscle fibers for repair and growth. MGF is produced naturally in response to mechanical stress on muscles.Binds to and disrupts microbial membranes through electrostatic interactions. Also binds to lipopolysaccharide (LPS) to neutralize endotoxins and has immunomodulatory effects.
Typical DosageResearch protocols typically use 200-400mcg injected into targeted muscle groups 2-3 times weekly, usually post-workout.Research applications vary widely. Oral lactoferrin supplements (containing lactoferricin precursor) typically dosed at 100-400mg daily.
AdministrationIntramuscular injection, ideally into muscles trained that day. Best administered post-workout when satellite cell activation is relevant.Available through lactoferrin supplementation orally. Purified lactoferricin primarily used in research settings.
Side EffectsInjection site soreness, potential hypoglycemia, and localized swelling. Generally well-tolerated.Lactoferrin supplementation is generally well-tolerated. May cause GI upset in some individuals. Derived from milk so caution with dairy allergies.
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Key Differences

Unique to PEG-MGF:

Unique to Lactoferricin:

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