Melanotan II vs Lactoferricin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Melanotan II

Melanotan II is a synthetic peptide analog of α-MSH with broader receptor activity than Melanotan I. It produces tanning effects and has notable effects on sexual function and appetite suppression.

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Lactoferricin

Lactoferricin is an antimicrobial peptide derived from lactoferrin, a protein found in milk and other secretions. It has potent antibacterial, antiviral, and antifungal properties.

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Side-by-Side Comparison

AspectMelanotan IILactoferricin
MechanismNon-selective melanocortin receptor agonist affecting MC1R (tanning), MC3R and MC4R (sexual function and appetite). This broader activity explains its multiple effects beyond tanning.Binds to and disrupts microbial membranes through electrostatic interactions. Also binds to lipopolysaccharide (LPS) to neutralize endotoxins and has immunomodulatory effects.
Typical DosageTypical protocols: 0.25-0.5mg daily during loading phase for 1-2 weeks, then 0.5-1mg before UV exposure for maintenance. Start low to assess tolerance.Research applications vary widely. Oral lactoferrin supplements (containing lactoferricin precursor) typically dosed at 100-400mg daily.
AdministrationSubcutaneous injection. Usually combined with UV exposure for tanning effects. Nasal spray formulations exist but have lower bioavailability.Available through lactoferrin supplementation orally. Purified lactoferricin primarily used in research settings.
Side EffectsNausea (common initially), facial flushing, spontaneous erections, increased libido, appetite suppression, and mole darkening.Lactoferrin supplementation is generally well-tolerated. May cause GI upset in some individuals. Derived from milk so caution with dairy allergies.
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Key Differences

Unique to Melanotan II:

Unique to Lactoferricin:

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