Leuphasyl vs Lactoferricin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Leuphasyl

Leuphasyl (Pentapeptide-18) is a cosmetic peptide that reduces muscle tension through a mechanism similar to enkephalins. Often combined with Syn-Ake for enhanced anti-wrinkle effects.

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Lactoferricin

Lactoferricin is an antimicrobial peptide derived from lactoferrin, a protein found in milk and other secretions. It has potent antibacterial, antiviral, and antifungal properties.

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Side-by-Side Comparison

AspectLeuphasylLactoferricin
MechanismMimics enkephalin and binds to enkephalin receptors on muscle cells, reducing acetylcholine release and thereby decreasing muscle contraction intensity.Binds to and disrupts microbial membranes through electrostatic interactions. Also binds to lipopolysaccharide (LPS) to neutralize endotoxins and has immunomodulatory effects.
Typical DosageTopical: 3-8% concentration in serums. Often used in combination products with other muscle-relaxing peptides.Research applications vary widely. Oral lactoferrin supplements (containing lactoferricin precursor) typically dosed at 100-400mg daily.
AdministrationTopical application to expression lines. Best results with consistent twice-daily use over 8+ weeks.Available through lactoferrin supplementation orally. Purified lactoferricin primarily used in research settings.
Side EffectsVery well-tolerated topically. No significant adverse effects reported at cosmetic concentrations.Lactoferrin supplementation is generally well-tolerated. May cause GI upset in some individuals. Derived from milk so caution with dairy allergies.
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Key Differences

Unique to Leuphasyl:

Unique to Lactoferricin:

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