Dihexa vs Lactoferricin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Dihexa

Dihexa is a nootropic peptide derived from angiotensin IV. It has shown remarkable cognitive-enhancing properties in animal studies, being described as potentially millions of times more potent than BDNF.

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Lactoferricin

Lactoferricin is an antimicrobial peptide derived from lactoferrin, a protein found in milk and other secretions. It has potent antibacterial, antiviral, and antifungal properties.

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Side-by-Side Comparison

AspectDihexaLactoferricin
MechanismActs as a hepatocyte growth factor (HGF) potentiator by binding to its receptor c-Met. Promotes synaptogenesis, neuronal survival, and cognitive enhancement through this pathway.Binds to and disrupts microbial membranes through electrostatic interactions. Also binds to lipopolysaccharide (LPS) to neutralize endotoxins and has immunomodulatory effects.
Typical DosageResearch dosing is highly variable due to extreme potency. Typical range: 10-40mg orally or sublingually. Start with lowest doses due to potency.Research applications vary widely. Oral lactoferrin supplements (containing lactoferricin precursor) typically dosed at 100-400mg daily.
AdministrationCan be taken orally, sublingually, or intranasally. Extremely potent - careful dosing is essential. Best used cyclically.Available through lactoferrin supplementation orally. Purified lactoferricin primarily used in research settings.
Side EffectsLimited human data. Reported effects include headache, temporary brain fog during adjustment, and potential mood changes.Lactoferrin supplementation is generally well-tolerated. May cause GI upset in some individuals. Derived from milk so caution with dairy allergies.
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Key Differences

Unique to Dihexa:

Unique to Lactoferricin:

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