Dihexa
Dihexa is a nootropic peptide derived from angiotensin IV. It has shown remarkable cognitive-enhancing properties in animal studies, being described as potentially millions of times more potent than BDNF.
Mechanism of Action
Acts as a hepatocyte growth factor (HGF) potentiator by binding to its receptor c-Met. Promotes synaptogenesis, neuronal survival, and cognitive enhancement through this pathway.
Typical Dosage (Research)
Research dosing is highly variable due to extreme potency. Typical range: 10-40mg orally or sublingually. Start with lowest doses due to potency.
Can be taken orally, sublingually, or intranasally. Extremely potent - careful dosing is essential. Best used cyclically.
Side Effects & Risks
Limited human data. Reported effects include headache, temporary brain fog during adjustment, and potential mood changes.
Very limited human research data. Theoretical concerns about promoting growth of existing cancers through HGF pathway. Long-term safety unknown.
Who Uses Dihexa
Researchers, advanced nootropic users, those with cognitive decline seeking experimental options.