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Thymulin vs NA-Selank Amidate

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymulin

Thymulin (Facteur Thymique Sérique) is a zinc-dependent nonapeptide hormone produced by thymic epithelial cells. It plays important roles in T-cell differentiation and immune system maturation.

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NA-Selank Amidate

NA-Selank Amidate (N-Acetyl Selank Amidate) is an enhanced version of Selank with improved stability and blood-brain barrier penetration. The modifications increase bioavailability and duration of cognitive and anxiolytic effects.

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Side-by-Side Comparison

AspectThymulinNA-Selank Amidate
MechanismRequires zinc for biological activity. Promotes T-cell differentiation, modulates cytokine production, and influences neuroendocrine function. Levels decline significantly with age.Same core mechanism as Selank - modulates BDNF, serotonin, and norepinephrine systems. The N-acetyl group improves membrane permeability while the amidate modification increases enzymatic stability.
Typical DosageResearch protocols vary. Often studied alongside zinc supplementation. Typical research doses in the microgram range.Intranasal: 100-400mcg 1-3 times daily. Lower doses needed compared to standard Selank due to enhanced bioavailability.
AdministrationSubcutaneous or intramuscular injection in research settings. Requires adequate zinc status for activity.Primarily intranasal administration. Can be used sublingually. More stable in solution than standard Selank.
Side EffectsLimited data on exogenous administration. Theoretical effects on immune function require monitoring.Generally well-tolerated. Possible mild fatigue or nasal irritation. Less frequent dosing needed than standard Selank.
Best For

What They Have in Common

Both Thymulin and NA-Selank Amidate are commonly used for:

Key Differences

Unique to Thymulin:

Unique to NA-Selank Amidate:

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