Thymosin Alpha-1 vs FGL

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymosin Alpha-1

Thymosin Alpha-1 is a peptide naturally produced by the thymus gland that plays a crucial role in immune system modulation. It is approved in over 35 countries for various conditions including hepatitis B and C.

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FGL

FGL (FG Loop) is a synthetic peptide that mimics the neural cell adhesion molecule (NCAM) FG loop region. It promotes neuroplasticity and has shown cognitive-enhancing effects in research.

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Side-by-Side Comparison

AspectThymosin Alpha-1FGL
MechanismEnhances T-cell function and maturation, stimulates dendritic cell activity, and modulates cytokine production. Promotes the differentiation of stem cells into mature T lymphocytes.Binds to FGFR1 (fibroblast growth factor receptor 1) to activate downstream signaling cascades that promote neurite outgrowth, synaptic plasticity, and neuronal survival.
Typical DosageClinical dosing typically ranges from 1.6mg to 6.4mg administered subcutaneously 2-3 times weekly. Research protocols may vary.Research protocols have used subcutaneous doses ranging from 1-10mg. Intranasal administration also studied. Optimal dosing not established.
AdministrationSubcutaneous injection. Often used in cycles or as part of comprehensive immune support protocols.Subcutaneous injection or intranasal administration. Research compound with limited human dosing data.
Side EffectsGenerally well-tolerated. Rare side effects include injection site reactions, mild flu-like symptoms, and temporary fatigue.Limited human data available. Animal studies show good tolerability.
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Key Differences

Unique to Thymosin Alpha-1:

Unique to FGL:

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