Thymosin Alpha-1 vs Alpha-Defensin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymosin Alpha-1

Thymosin Alpha-1 is a peptide naturally produced by the thymus gland that plays a crucial role in immune system modulation. It is approved in over 35 countries for various conditions including hepatitis B and C.

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Alpha-Defensin

Alpha-defensins are small cationic peptides that are key components of the innate immune system. They have broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses.

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Side-by-Side Comparison

AspectThymosin Alpha-1Alpha-Defensin
MechanismEnhances T-cell function and maturation, stimulates dendritic cell activity, and modulates cytokine production. Promotes the differentiation of stem cells into mature T lymphocytes.Insert into microbial membranes to form pores, leading to cell death. Also have immunomodulatory effects including chemotaxis of immune cells and cytokine modulation.
Typical DosageClinical dosing typically ranges from 1.6mg to 6.4mg administered subcutaneously 2-3 times weekly. Research protocols may vary.Research compound - dosing varies by application. Typically studied in laboratory and early clinical research settings rather than for general use.
AdministrationSubcutaneous injection. Often used in cycles or as part of comprehensive immune support protocols.Various routes studied including topical, local injection, and systemic administration depending on application.
Side EffectsGenerally well-tolerated. Rare side effects include injection site reactions, mild flu-like symptoms, and temporary fatigue.Limited human use data. May cause local inflammation. Potential for immune activation effects.
Best For

What They Have in Common

Both Thymosin Alpha-1 and Alpha-Defensin are commonly used for:

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