Thymalin vs Mod GRF 1-29

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymalin

Thymalin is a polypeptide preparation derived from calf thymus. Developed in Russia, it has been used for decades to support immune function and has shown potential anti-aging effects in long-term studies.

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Mod GRF 1-29

Mod GRF 1-29 (Modified GRF 1-29, also called CJC-1295 without DAC or Tetrasubstituted GRF 1-29) is a modified growth hormone-releasing hormone analog with improved stability over natural GHRH.

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Side-by-Side Comparison

AspectThymalinMod GRF 1-29
MechanismRegulates the ratio of T-cell subpopulations, stimulates cellular immunity, and enhances phagocytosis. Also affects neuroendocrine regulation and may influence melatonin production.Binds to GHRH receptors in the pituitary gland to stimulate growth hormone release. Four amino acid substitutions improve resistance to enzymatic degradation while maintaining biological activity.
Typical DosageClinical protocols: 5-20mg daily intramuscularly for 3-10 days. Often cycled 1-2 times per year for maintenance.Typical dosing: 100-300mcg administered 2-3 times daily, usually combined with a GHRP like Ipamorelin for synergistic effects.
AdministrationIntramuscular injection. Usually administered in short courses rather than continuously. Often combined with Epithalamin for anti-aging protocols.Subcutaneous injection. Best administered on empty stomach. Short half-life (~30 minutes) necessitates multiple daily doses, unlike DAC version.
Side EffectsGenerally well-tolerated. May cause injection site reactions or temporary flu-like symptoms as immune function is modulated.Flushing, headache, dizziness, and injection site reactions. Generally well-tolerated. May cause water retention.
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Key Differences

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