Thymalin vs MGF (Mechano Growth Factor)

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymalin

Thymalin is a polypeptide preparation derived from calf thymus. Developed in Russia, it has been used for decades to support immune function and has shown potential anti-aging effects in long-term studies.

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MGF (Mechano Growth Factor)

MGF (Mechano Growth Factor) is a splice variant of IGF-1 that is produced locally in muscle tissue in response to mechanical stress. The non-PEGylated form has a very short half-life.

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Side-by-Side Comparison

AspectThymalinMGF (Mechano Growth Factor)
MechanismRegulates the ratio of T-cell subpopulations, stimulates cellular immunity, and enhances phagocytosis. Also affects neuroendocrine regulation and may influence melatonin production.Activates muscle satellite cells (stem cells) and promotes their proliferation without differentiation, priming them for fusion with existing muscle fibers during repair and growth.
Typical DosageClinical protocols: 5-20mg daily intramuscularly for 3-10 days. Often cycled 1-2 times per year for maintenance.Due to extremely short half-life (minutes), typical protocols use 100-200mcg injected directly into target muscles immediately post-workout.
AdministrationIntramuscular injection. Usually administered in short courses rather than continuously. Often combined with Epithalamin for anti-aging protocols.Intramuscular injection into trained muscles within minutes of workout completion. Must be used immediately after reconstitution due to instability.
Side EffectsGenerally well-tolerated. May cause injection site reactions or temporary flu-like symptoms as immune function is modulated.Injection site soreness, potential hypoglycemia, localized swelling. Short half-life limits systemic effects.
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Key Differences

Unique to Thymalin:

Unique to MGF (Mechano Growth Factor):

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