Thymalin vs Human Growth Hormone (HGH)

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymalin

Thymalin is a polypeptide preparation derived from calf thymus. Developed in Russia, it has been used for decades to support immune function and has shown potential anti-aging effects in long-term studies.

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Human Growth Hormone (HGH)

Human Growth Hormone (somatropin) is a 191-amino acid protein identical to naturally produced GH. FDA-approved for growth hormone deficiency, Turner syndrome, and other conditions. Widely used off-label for anti-aging and performance.

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Side-by-Side Comparison

AspectThymalinHuman Growth Hormone (HGH)
MechanismRegulates the ratio of T-cell subpopulations, stimulates cellular immunity, and enhances phagocytosis. Also affects neuroendocrine regulation and may influence melatonin production.Binds to GH receptors throughout the body, stimulating IGF-1 production in the liver. Promotes protein synthesis, fat metabolism, and cellular regeneration across multiple tissues.
Typical DosageClinical protocols: 5-20mg daily intramuscularly for 3-10 days. Often cycled 1-2 times per year for maintenance.Medical: 0.1-0.3mg/kg/week divided into daily doses. Anti-aging: 1-2 IU daily. Performance: 2-6 IU daily, sometimes higher.
AdministrationIntramuscular injection. Usually administered in short courses rather than continuously. Often combined with Epithalamin for anti-aging protocols.Subcutaneous injection, preferably at night to mimic natural pulsatile release. Rotate injection sites. Store refrigerated.
Side EffectsGenerally well-tolerated. May cause injection site reactions or temporary flu-like symptoms as immune function is modulated.Joint pain, water retention, carpal tunnel syndrome, potential insulin resistance, and acromegaly features with long-term high doses.
Best For

What They Have in Common

Both Thymalin and Human Growth Hormone (HGH) are commonly used for:

Key Differences

Unique to Thymalin:

Unique to Human Growth Hormone (HGH):

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