Thymalin vs Alpha-Defensin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymalin

Thymalin is a polypeptide preparation derived from calf thymus. Developed in Russia, it has been used for decades to support immune function and has shown potential anti-aging effects in long-term studies.

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Alpha-Defensin

Alpha-defensins are small cationic peptides that are key components of the innate immune system. They have broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses.

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Side-by-Side Comparison

AspectThymalinAlpha-Defensin
MechanismRegulates the ratio of T-cell subpopulations, stimulates cellular immunity, and enhances phagocytosis. Also affects neuroendocrine regulation and may influence melatonin production.Insert into microbial membranes to form pores, leading to cell death. Also have immunomodulatory effects including chemotaxis of immune cells and cytokine modulation.
Typical DosageClinical protocols: 5-20mg daily intramuscularly for 3-10 days. Often cycled 1-2 times per year for maintenance.Research compound - dosing varies by application. Typically studied in laboratory and early clinical research settings rather than for general use.
AdministrationIntramuscular injection. Usually administered in short courses rather than continuously. Often combined with Epithalamin for anti-aging protocols.Various routes studied including topical, local injection, and systemic administration depending on application.
Side EffectsGenerally well-tolerated. May cause injection site reactions or temporary flu-like symptoms as immune function is modulated.Limited human use data. May cause local inflammation. Potential for immune activation effects.
Best For

What They Have in Common

Both Thymalin and Alpha-Defensin are commonly used for:

Key Differences

Unique to Thymalin:

Unique to Alpha-Defensin:

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