SS-31 (Elamipretide) vs Thymulin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

SS-31 (Elamipretide)

SS-31, also known as Elamipretide or Bendavia, is a mitochondria-targeted tetrapeptide. It has been studied extensively for mitochondrial diseases, heart failure, and age-related decline in mitochondrial function.

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Thymulin

Thymulin (Facteur Thymique Sérique) is a zinc-dependent nonapeptide hormone produced by thymic epithelial cells. It plays important roles in T-cell differentiation and immune system maturation.

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Side-by-Side Comparison

Aspect	SS-31 (Elamipretide)	Thymulin
Dose Range	20 mg–40 mg	100 mcg–400 mcg
Frequency	1x daily	1x daily
Cycle Length	4–12 weeks	4–8 weeks
Route	subcutaneous	subcutaneous
Mechanism	Concentrates in the inner mitochondrial membrane where it binds to cardiolipin, stabilizing electron transport chain function, reducing reactive oxygen species, and improving ATP production efficiency.	Requires zinc for biological activity. Promotes T-cell differentiation, modulates cytokine production, and influences neuroendocrine function. Levels decline significantly with age.
Typical Dosage	Clinical trials have used IV infusions of 0.25mg/kg for acute conditions. Subcutaneous dosing protocols for research use typically range from 1-5mg daily.	Research protocols vary. Often studied alongside zinc supplementation. Typical research doses in the microgram range.
Administration	Can be administered IV or subcutaneously. Most clinical research has used IV administration for cardiac conditions.	Subcutaneous or intramuscular injection in research settings. Requires adequate zinc status for activity.
Side Effects	Generally well-tolerated. Clinical trials reported injection site reactions and occasional headache.	Limited data on exogenous administration. Theoretical effects on immune function require monitoring.
Best For	Recovery & Healing Anti-Aging & Longevity	Immune Support Anti-Aging & Longevity