Semax vs Thymulin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Semax

Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone). Developed in Russia as a nootropic and neuroprotective agent.

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Thymulin

Thymulin (Facteur Thymique Sérique) is a zinc-dependent nonapeptide hormone produced by thymic epithelial cells. It plays important roles in T-cell differentiation and immune system maturation.

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Side-by-Side Comparison

AspectSemaxThymulin
MechanismEnhances BDNF expression, modulates dopamine and serotonin systems, and provides neuroprotective effects. Increases attention, memory formation, and learning.Requires zinc for biological activity. Promotes T-cell differentiation, modulates cytokine production, and influences neuroendocrine function. Levels decline significantly with age.
Typical DosageIntranasal: 200-600mcg 2-3 times daily. Higher doses (up to 1mg) used in clinical settings for stroke recovery.Research protocols vary. Often studied alongside zinc supplementation. Typical research doses in the microgram range.
AdministrationPrimarily administered intranasally. N-Acetyl Semax Amidate (NASA) is a modified version with enhanced stability and potency.Subcutaneous or intramuscular injection in research settings. Requires adequate zinc status for activity.
Side EffectsGenerally well-tolerated. May cause mild irritability or hair shedding in some users.Limited data on exogenous administration. Theoretical effects on immune function require monitoring.
Best For

What They Have in Common

Both Semax and Thymulin are commonly used for:

Key Differences

Unique to Semax:

Unique to Thymulin:

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