Semax vs Thymalin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Semax

Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone). Developed in Russia as a nootropic and neuroprotective agent.

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Thymalin

Thymalin is a polypeptide preparation derived from calf thymus. Developed in Russia, it has been used for decades to support immune function and has shown potential anti-aging effects in long-term studies.

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Side-by-Side Comparison

AspectSemaxThymalin
MechanismEnhances BDNF expression, modulates dopamine and serotonin systems, and provides neuroprotective effects. Increases attention, memory formation, and learning.Regulates the ratio of T-cell subpopulations, stimulates cellular immunity, and enhances phagocytosis. Also affects neuroendocrine regulation and may influence melatonin production.
Typical DosageIntranasal: 200-600mcg 2-3 times daily. Higher doses (up to 1mg) used in clinical settings for stroke recovery.Clinical protocols: 5-20mg daily intramuscularly for 3-10 days. Often cycled 1-2 times per year for maintenance.
AdministrationPrimarily administered intranasally. N-Acetyl Semax Amidate (NASA) is a modified version with enhanced stability and potency.Intramuscular injection. Usually administered in short courses rather than continuously. Often combined with Epithalamin for anti-aging protocols.
Side EffectsGenerally well-tolerated. May cause mild irritability or hair shedding in some users.Generally well-tolerated. May cause injection site reactions or temporary flu-like symptoms as immune function is modulated.
Best For

What They Have in Common

Both Semax and Thymalin are commonly used for:

Key Differences

Unique to Semax:

Unique to Thymalin:

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