Semax vs NA-Semax Amidate
A detailed comparison to help you understand the differences and choose the right peptide for your research goals.
Semax
Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone). Developed in Russia as a nootropic and neuroprotective agent.
Full details →NA-Semax Amidate
NA-Semax Amidate (N-Acetyl Semax Amidate) is a modified version of Semax with enhanced stability and potency. Also known as NASA, it provides stronger and longer-lasting nootropic effects than standard Semax.
Full details →Side-by-Side Comparison
| Aspect | Semax | NA-Semax Amidate |
|---|---|---|
| Mechanism | Enhances BDNF expression, modulates dopamine and serotonin systems, and provides neuroprotective effects. Increases attention, memory formation, and learning. | Maintains Semax's core actions on BDNF, NGF, and monoamine systems with improved pharmacokinetics. The modifications enhance CNS penetration and extend duration of action. |
| Typical Dosage | Intranasal: 200-600mcg 2-3 times daily. Higher doses (up to 1mg) used in clinical settings for stroke recovery. | Intranasal: 100-600mcg 1-2 times daily. Start with lower doses as it's more potent than standard Semax. |
| Administration | Primarily administered intranasally. N-Acetyl Semax Amidate (NASA) is a modified version with enhanced stability and potency. | Intranasal spray is most common. Can be used sublingually. More stable than standard Semax in solution. |
| Side Effects | Generally well-tolerated. May cause mild irritability or hair shedding in some users. | May cause irritability, hair shedding (rare), or overstimulation at high doses. Generally well-tolerated. |
| Best For |
What They Have in Common
Both Semax and NA-Semax Amidate are commonly used for: