Selank vs PEG-MGF

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Selank

Selank is a synthetic peptide derived from the naturally occurring immunomodulatory peptide tuftsin. Developed in Russia for anxiety and cognitive enhancement.

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PEG-MGF

PEG-MGF (PEGylated Mechano Growth Factor) is a variant of IGF-1 that is produced in response to muscle damage. PEGylation extends its half-life from minutes to several hours, making it practical for use.

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Side-by-Side Comparison

AspectSelankPEG-MGF
MechanismModulates the expression of brain-derived neurotrophic factor (BDNF) and affects serotonin and norepinephrine systems. Has immunomodulatory and anxiolytic properties.Activates muscle satellite cells (stem cells) and promotes their fusion to existing muscle fibers for repair and growth. MGF is produced naturally in response to mechanical stress on muscles.
Typical DosageIntranasal administration: 250-500mcg 2-3 times daily. Subcutaneous: 250-500mcg daily.Research protocols typically use 200-400mcg injected into targeted muscle groups 2-3 times weekly, usually post-workout.
AdministrationMost commonly administered intranasally for cognitive effects. Can also be injected subcutaneously.Intramuscular injection, ideally into muscles trained that day. Best administered post-workout when satellite cell activation is relevant.
Side EffectsGenerally well-tolerated. Some users report mild fatigue or nasal irritation with intranasal use.Injection site soreness, potential hypoglycemia, and localized swelling. Generally well-tolerated.
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Key Differences

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