Selank vs MGF (Mechano Growth Factor)

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Selank

Selank is a synthetic peptide derived from the naturally occurring immunomodulatory peptide tuftsin. Developed in Russia for anxiety and cognitive enhancement.

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MGF (Mechano Growth Factor)

MGF (Mechano Growth Factor) is a splice variant of IGF-1 that is produced locally in muscle tissue in response to mechanical stress. The non-PEGylated form has a very short half-life.

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Side-by-Side Comparison

AspectSelankMGF (Mechano Growth Factor)
MechanismModulates the expression of brain-derived neurotrophic factor (BDNF) and affects serotonin and norepinephrine systems. Has immunomodulatory and anxiolytic properties.Activates muscle satellite cells (stem cells) and promotes their proliferation without differentiation, priming them for fusion with existing muscle fibers during repair and growth.
Typical DosageIntranasal administration: 250-500mcg 2-3 times daily. Subcutaneous: 250-500mcg daily.Due to extremely short half-life (minutes), typical protocols use 100-200mcg injected directly into target muscles immediately post-workout.
AdministrationMost commonly administered intranasally for cognitive effects. Can also be injected subcutaneously.Intramuscular injection into trained muscles within minutes of workout completion. Must be used immediately after reconstitution due to instability.
Side EffectsGenerally well-tolerated. Some users report mild fatigue or nasal irritation with intranasal use.Injection site soreness, potential hypoglycemia, localized swelling. Short half-life limits systemic effects.
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Key Differences

Unique to Selank:

Unique to MGF (Mechano Growth Factor):

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