PEG-MGF vs Thymalin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

PEG-MGF

PEG-MGF (PEGylated Mechano Growth Factor) is a variant of IGF-1 that is produced in response to muscle damage. PEGylation extends its half-life from minutes to several hours, making it practical for use.

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Thymalin

Thymalin is a polypeptide preparation derived from calf thymus. Developed in Russia, it has been used for decades to support immune function and has shown potential anti-aging effects in long-term studies.

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Side-by-Side Comparison

AspectPEG-MGFThymalin
MechanismActivates muscle satellite cells (stem cells) and promotes their fusion to existing muscle fibers for repair and growth. MGF is produced naturally in response to mechanical stress on muscles.Regulates the ratio of T-cell subpopulations, stimulates cellular immunity, and enhances phagocytosis. Also affects neuroendocrine regulation and may influence melatonin production.
Typical DosageResearch protocols typically use 200-400mcg injected into targeted muscle groups 2-3 times weekly, usually post-workout.Clinical protocols: 5-20mg daily intramuscularly for 3-10 days. Often cycled 1-2 times per year for maintenance.
AdministrationIntramuscular injection, ideally into muscles trained that day. Best administered post-workout when satellite cell activation is relevant.Intramuscular injection. Usually administered in short courses rather than continuously. Often combined with Epithalamin for anti-aging protocols.
Side EffectsInjection site soreness, potential hypoglycemia, and localized swelling. Generally well-tolerated.Generally well-tolerated. May cause injection site reactions or temporary flu-like symptoms as immune function is modulated.
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Key Differences

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