Palmitoyl Tetrapeptide-7 vs Lactoferricin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Palmitoyl Tetrapeptide-7

Palmitoyl Tetrapeptide-7 is an anti-inflammatory peptide that reduces IL-6 secretion. Combined with Palmitoyl Tripeptide-1, it forms Matrixyl 3000, addressing both collagen production and inflammation.

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Lactoferricin

Lactoferricin is an antimicrobial peptide derived from lactoferrin, a protein found in milk and other secretions. It has potent antibacterial, antiviral, and antifungal properties.

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Side-by-Side Comparison

AspectPalmitoyl Tetrapeptide-7Lactoferricin
MechanismSuppresses interleukin-6 (IL-6) production, reducing inflammation that contributes to skin aging. The anti-inflammatory effect complements collagen-stimulating peptides.Binds to and disrupts microbial membranes through electrostatic interactions. Also binds to lipopolysaccharide (LPS) to neutralize endotoxins and has immunomodulatory effects.
Typical DosageTopical: Usually combined with Palmitoyl Tripeptide-1 at similar concentrations (2-4%) in the Matrixyl 3000 complex.Research applications vary widely. Oral lactoferrin supplements (containing lactoferricin precursor) typically dosed at 100-400mg daily.
AdministrationTopical application with other anti-aging actives. The palmitoyl group enhances delivery into the skin.Available through lactoferrin supplementation orally. Purified lactoferricin primarily used in research settings.
Side EffectsExcellent tolerability profile. Anti-inflammatory properties may actually soothe sensitive skin.Lactoferrin supplementation is generally well-tolerated. May cause GI upset in some individuals. Derived from milk so caution with dairy allergies.
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Key Differences

Unique to Palmitoyl Tetrapeptide-7:

Unique to Lactoferricin:

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