Mod GRF 1-29 vs Thymulin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Mod GRF 1-29

Mod GRF 1-29 (Modified GRF 1-29, also called CJC-1295 without DAC or Tetrasubstituted GRF 1-29) is a modified growth hormone-releasing hormone analog with improved stability over natural GHRH.

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Thymulin

Thymulin (Facteur Thymique Sérique) is a zinc-dependent nonapeptide hormone produced by thymic epithelial cells. It plays important roles in T-cell differentiation and immune system maturation.

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Side-by-Side Comparison

AspectMod GRF 1-29Thymulin
MechanismBinds to GHRH receptors in the pituitary gland to stimulate growth hormone release. Four amino acid substitutions improve resistance to enzymatic degradation while maintaining biological activity.Requires zinc for biological activity. Promotes T-cell differentiation, modulates cytokine production, and influences neuroendocrine function. Levels decline significantly with age.
Typical DosageTypical dosing: 100-300mcg administered 2-3 times daily, usually combined with a GHRP like Ipamorelin for synergistic effects.Research protocols vary. Often studied alongside zinc supplementation. Typical research doses in the microgram range.
AdministrationSubcutaneous injection. Best administered on empty stomach. Short half-life (~30 minutes) necessitates multiple daily doses, unlike DAC version.Subcutaneous or intramuscular injection in research settings. Requires adequate zinc status for activity.
Side EffectsFlushing, headache, dizziness, and injection site reactions. Generally well-tolerated. May cause water retention.Limited data on exogenous administration. Theoretical effects on immune function require monitoring.
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Key Differences

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