KPV vs Adamax

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

KPV

KPV is a tripeptide (Lys-Pro-Val) derived from alpha-melanocyte-stimulating hormone (α-MSH). It retains the potent anti-inflammatory properties of the parent hormone without the tanning or other melanocortin effects.

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Adamax

Adamax is a modified version of Semax with an adamantane group attached, designed to enhance its nootropic effects and extend duration of action compared to standard Semax.

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Side-by-Side Comparison

AspectKPVAdamax
MechanismInhibits NF-κB activation and reduces inflammatory cytokine production. Enters cells and directly modulates inflammatory signaling without requiring melanocortin receptors.Similar to Semax - enhances BDNF expression and modulates dopamine/serotonin systems. The adamantane modification may increase lipophilicity and CNS penetration.
Typical DosageOral/sublingual: 200-500mcg 1-3 times daily. Topical formulations for localized inflammation. Also used in enemas for gut inflammation.Intranasal: 100-500mcg 1-2 times daily. Lower doses than standard Semax may be effective due to enhanced potency.
AdministrationCan be taken orally, sublingually, or as suppositories/enemas for gut inflammation. Topical use for skin conditions. Stable orally unlike most peptides.Intranasal spray is most common route. More stable than standard Semax. Often used for acute cognitive enhancement.
Side EffectsGenerally very well-tolerated. Minimal systemic effects due to targeted anti-inflammatory action.Similar to Semax - possible irritability, hair shedding, or overstimulation. May have stronger effects than standard Semax.
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Key Differences

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