Hexarelin vs Gonadorelin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Hexarelin

Hexarelin is a potent synthetic hexapeptide growth hormone secretagogue. It provides the strongest GH release among GHRPs but is associated with rapid desensitization of receptors.

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Gonadorelin

Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH). It stimulates the pituitary to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), supporting natural hormone production.

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Side-by-Side Comparison

AspectHexarelinGonadorelin
MechanismActs as a ghrelin mimetic with high potency at the GHS receptor. Provides powerful GH release but receptor desensitization occurs faster than with other GHRPs, requiring cycling.Binds to GnRH receptors in the pituitary gland, triggering pulsatile release of LH and FSH. This stimulates testicular or ovarian function and natural sex hormone production.
Typical DosageTypical dosing: 100-200mcg administered 2-3 times daily for 4-6 weeks, followed by an equal off period to allow receptor resensitization.Men: 100-200mcg subcutaneously 2-3 times daily. Women (fertility): Per clinical protocol. HRT support: Often combined with other therapies.
AdministrationSubcutaneous injection. Cycling is essential to maintain effectiveness. Often used in short bursts rather than continuous protocols.Subcutaneous injection. Pulsatile administration mimics natural GnRH release patterns. Often used during or after testosterone therapy.
Side EffectsWater retention, cortisol and prolactin increase, hunger (moderate), tingling, and potential blood pressure effects.Headache, flushing, injection site reactions. In women may cause ovarian hyperstimulation. Generally well-tolerated.
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Key Differences

Unique to Hexarelin:

Unique to Gonadorelin:

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