GHRP-2 vs MGF (Mechano Growth Factor)

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

GHRP-2

Growth Hormone Releasing Peptide 2 (GHRP-2) is considered one of the most potent GHRPs available. It provides strong GH release with moderate hunger increase compared to GHRP-6.

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MGF (Mechano Growth Factor)

MGF (Mechano Growth Factor) is a splice variant of IGF-1 that is produced locally in muscle tissue in response to mechanical stress. The non-PEGylated form has a very short half-life.

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Side-by-Side Comparison

AspectGHRP-2MGF (Mechano Growth Factor)
MechanismBinds to the ghrelin receptor (GHS-R) to stimulate GH release from the pituitary. Also has some direct effects on the hypothalamus. Causes less appetite increase than GHRP-6.Activates muscle satellite cells (stem cells) and promotes their proliferation without differentiation, priming them for fusion with existing muscle fibers during repair and growth.
Typical DosageTypical dosing: 100-300mcg administered 2-3 times daily. Often stacked with GHRH peptides for enhanced GH release.Due to extremely short half-life (minutes), typical protocols use 100-200mcg injected directly into target muscles immediately post-workout.
AdministrationSubcutaneous injection on an empty stomach. Can be used at bedtime to enhance natural GH pulse during sleep.Intramuscular injection into trained muscles within minutes of workout completion. Must be used immediately after reconstitution due to instability.
Side EffectsModerate hunger increase, water retention, potential prolactin and cortisol elevation (less than GHRP-6), tingling sensations.Injection site soreness, potential hypoglycemia, localized swelling. Short half-life limits systemic effects.
Best For

What They Have in Common

Both GHRP-2 and MGF (Mechano Growth Factor) are commonly used for:

Key Differences

Unique to GHRP-2:

Unique to MGF (Mechano Growth Factor):

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