AHK-Cu vs Alpha-Defensin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

AHK-Cu

AHK-Cu (Copper Tripeptide-3, Alanine-Histidine-Lysine Copper) is a copper peptide similar to GHK-Cu but with different properties. It's used for hair growth and skin rejuvenation applications.

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Alpha-Defensin

Alpha-defensins are small cationic peptides that are key components of the innate immune system. They have broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses.

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Side-by-Side Comparison

AspectAHK-CuAlpha-Defensin
MechanismThe copper-binding tripeptide stimulates collagen synthesis and may promote hair follicle enlargement. Works similarly to GHK-Cu but may have distinct receptor interactions.Insert into microbial membranes to form pores, leading to cell death. Also have immunomodulatory effects including chemotaxis of immune cells and cytokine modulation.
Typical DosageTopical: 0.5-2% concentration in serums for skin or scalp applications. Often combined with other growth factors for hair formulations.Research compound - dosing varies by application. Typically studied in laboratory and early clinical research settings rather than for general use.
AdministrationTopical application to skin or scalp. Can be used with microneedling for enhanced penetration. May cause temporary blue-green tint at high concentrations.Various routes studied including topical, local injection, and systemic administration depending on application.
Side EffectsGenerally well-tolerated. May cause skin irritation in sensitive individuals. Temporary discoloration possible.Limited human use data. May cause local inflammation. Potential for immune activation effects.
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Key Differences

Unique to AHK-Cu:

Unique to Alpha-Defensin:

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