Tirzepatide vs Thymulin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Tirzepatide

Tirzepatide is a first-in-class dual GIP/GLP-1 receptor agonist. FDA-approved as Mounjaro (diabetes) and Zepbound (weight loss), it has shown superior weight loss results compared to semaglutide in clinical trials.

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Thymulin

Thymulin (Facteur Thymique Sérique) is a zinc-dependent nonapeptide hormone produced by thymic epithelial cells. It plays important roles in T-cell differentiation and immune system maturation.

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Side-by-Side Comparison

AspectTirzepatideThymulin
MechanismActivates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors, providing synergistic effects on insulin secretion, appetite suppression, and metabolic regulation. The dual mechanism may explain its enhanced efficacy.Requires zinc for biological activity. Promotes T-cell differentiation, modulates cytokine production, and influences neuroendocrine function. Levels decline significantly with age.
Typical DosageStart at 2.5mg weekly, titrate every 4 weeks through 5mg, 7.5mg, 10mg, 12.5mg, to maximum 15mg weekly. Full titration takes approximately 20 weeks.Research protocols vary. Often studied alongside zinc supplementation. Typical research doses in the microgram range.
AdministrationSubcutaneous injection once weekly. Rotate injection sites. Slower titration may help reduce GI side effects.Subcutaneous or intramuscular injection in research settings. Requires adequate zinc status for activity.
Side EffectsSimilar to semaglutide: nausea, diarrhea, vomiting, constipation, abdominal pain, decreased appetite. Generally improve with continued use.Limited data on exogenous administration. Theoretical effects on immune function require monitoring.
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Key Differences

Unique to Tirzepatide:

Unique to Thymulin:

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