Thymosin Alpha-1 vs Thymalin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymosin Alpha-1

Thymosin Alpha-1 is a peptide naturally produced by the thymus gland that plays a crucial role in immune system modulation. It is approved in over 35 countries for various conditions including hepatitis B and C.

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Thymalin

Thymalin is a polypeptide preparation derived from calf thymus. Developed in Russia, it has been used for decades to support immune function and has shown potential anti-aging effects in long-term studies.

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Side-by-Side Comparison

AspectThymosin Alpha-1Thymalin
MechanismEnhances T-cell function and maturation, stimulates dendritic cell activity, and modulates cytokine production. Promotes the differentiation of stem cells into mature T lymphocytes.Regulates the ratio of T-cell subpopulations, stimulates cellular immunity, and enhances phagocytosis. Also affects neuroendocrine regulation and may influence melatonin production.
Typical DosageClinical dosing typically ranges from 1.6mg to 6.4mg administered subcutaneously 2-3 times weekly. Research protocols may vary.Clinical protocols: 5-20mg daily intramuscularly for 3-10 days. Often cycled 1-2 times per year for maintenance.
AdministrationSubcutaneous injection. Often used in cycles or as part of comprehensive immune support protocols.Intramuscular injection. Usually administered in short courses rather than continuously. Often combined with Epithalamin for anti-aging protocols.
Side EffectsGenerally well-tolerated. Rare side effects include injection site reactions, mild flu-like symptoms, and temporary fatigue.Generally well-tolerated. May cause injection site reactions or temporary flu-like symptoms as immune function is modulated.
Best For

What They Have in Common

Both Thymosin Alpha-1 and Thymalin are commonly used for:

Key Differences

Unique to Thymosin Alpha-1:

Unique to Thymalin:

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