Thymosin Alpha-1 vs Tesamorelin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Thymosin Alpha-1

Thymosin Alpha-1 is a peptide naturally produced by the thymus gland that plays a crucial role in immune system modulation. It is approved in over 35 countries for various conditions including hepatitis B and C.

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Tesamorelin

Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH). It is FDA-approved under the brand name Egrifta for reducing excess abdominal fat in HIV-infected patients with lipodystrophy.

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Side-by-Side Comparison

AspectThymosin Alpha-1Tesamorelin
MechanismEnhances T-cell function and maturation, stimulates dendritic cell activity, and modulates cytokine production. Promotes the differentiation of stem cells into mature T lymphocytes.Stimulates the pituitary gland to produce and release growth hormone by binding to GHRH receptors. Increases IGF-1 levels which promotes lipolysis and reduces visceral adipose tissue.
Typical DosageClinical dosing typically ranges from 1.6mg to 6.4mg administered subcutaneously 2-3 times weekly. Research protocols may vary.FDA-approved dose: 2mg administered subcutaneously once daily. Research protocols may use various dosing schedules.
AdministrationSubcutaneous injection. Often used in cycles or as part of comprehensive immune support protocols.Subcutaneous injection into the abdomen. Rotate injection sites. Best administered at the same time daily, preferably in the evening.
Side EffectsGenerally well-tolerated. Rare side effects include injection site reactions, mild flu-like symptoms, and temporary fatigue.Common side effects include injection site reactions (erythema, pruritus), joint pain, peripheral edema, and muscle pain. May cause elevated blood glucose.
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Key Differences

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