Syn-Ake vs Selank
A detailed comparison to help you understand the differences and choose the right peptide for your research goals.
Syn-Ake
Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate) is a synthetic tripeptide that mimics the effect of Waglerin-1, a peptide found in Temple Viper venom. It's used in cosmetics for anti-wrinkle effects.
Full details →Selank
Selank is a synthetic peptide derived from the naturally occurring immunomodulatory peptide tuftsin. Developed in Russia for anxiety and cognitive enhancement.
Full details →Side-by-Side Comparison
| Aspect | Syn-Ake | Selank |
|---|---|---|
| Mechanism | Acts as a competitive antagonist at the nicotinic acetylcholine receptor, reducing muscle contractions similar to Botox but through a different mechanism. Provides muscle-relaxing effects when applied topically. | Modulates the expression of brain-derived neurotrophic factor (BDNF) and affects serotonin and norepinephrine systems. Has immunomodulatory and anxiolytic properties. |
| Typical Dosage | Topical: 1-4% concentration in serums or creams. Applied 1-2 times daily to target areas like forehead and crow's feet. | Intranasal administration: 250-500mcg 2-3 times daily. Subcutaneous: 250-500mcg daily. |
| Administration | Topical application only. Should be applied to clean skin. Often combined with other anti-aging peptides for synergistic effects. | Most commonly administered intranasally for cognitive effects. Can also be injected subcutaneously. |
| Side Effects | Generally well-tolerated topically. Rare reports of mild skin irritation or sensitivity. | Generally well-tolerated. Some users report mild fatigue or nasal irritation with intranasal use. |
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