SNAP-8 vs Epigen
A detailed comparison to help you understand the differences and choose the right peptide for your research goals.
SNAP-8
SNAP-8 (Acetyl Octapeptide-3) is a cosmetic peptide that reduces the appearance of wrinkles by modulating muscle contraction. It is often called 'topical Botox' though it works through a different mechanism.
Full details →Epigen
Epigen is a member of the epidermal growth factor (EGF) family. It plays roles in skin regeneration and has been studied for wound healing and anti-aging applications.
Full details →Side-by-Side Comparison
| Aspect | SNAP-8 | Epigen |
|---|---|---|
| Mechanism | Mimics the N-terminal end of SNAP-25, competing with native SNAP-25 for position in the SNARE complex. This reduces neurotransmitter release at the neuromuscular junction, decreasing muscle contraction. | Binds to and activates the EGF receptor (EGFR), promoting cell proliferation, migration, and differentiation. Involved in skin homeostasis and repair processes. |
| Typical Dosage | Topical: 3-10% concentration in serums or creams, applied 1-2 times daily to target areas (forehead, crow's feet, etc.). | Topical: Typically used at low concentrations (ppm to low %) in cosmetic formulations. Research applications vary. |
| Administration | Topical application only. Should be applied to clean skin. Often formulated with penetration enhancers for better absorption. | Primarily topical application for skincare. Research may use other routes for systemic effects. |
| Side Effects | Generally well-tolerated topically. Rare reports of mild skin irritation. No systemic effects at cosmetic doses. | Topical use generally well-tolerated. Theoretical concerns about promoting cell proliferation. |
| Best For |
What They Have in Common
Both SNAP-8 and Epigen are commonly used for: