Semax vs Epitalon
A detailed comparison to help you understand the differences and choose the right peptide for your research goals.
Semax
Semax is a synthetic peptide derived from ACTH (adrenocorticotropic hormone). Developed in Russia as a nootropic and neuroprotective agent.
Full details →Epitalon
Epitalon (Epithalon) is a synthetic tetrapeptide based on the natural peptide epithalamin, produced by the pineal gland. It is primarily studied for its effects on telomerase activation.
Full details →Side-by-Side Comparison
| Aspect | Semax | Epitalon |
|---|---|---|
| Mechanism | Enhances BDNF expression, modulates dopamine and serotonin systems, and provides neuroprotective effects. Increases attention, memory formation, and learning. | Stimulates telomerase production, which can lengthen telomeres on DNA strands. May also regulate melatonin production and circadian rhythms. |
| Typical Dosage | Intranasal: 200-600mcg 2-3 times daily. Higher doses (up to 1mg) used in clinical settings for stroke recovery. | Typical protocols: 5-10mg daily for 10-20 days, repeated 2-3 times per year. |
| Administration | Primarily administered intranasally. N-Acetyl Semax Amidate (NASA) is a modified version with enhanced stability and potency. | Subcutaneous or intramuscular injection. Usually administered in cycles rather than continuously. |
| Side Effects | Generally well-tolerated. May cause mild irritability or hair shedding in some users. | Generally well-tolerated. May affect sleep patterns initially. |
| Best For |
Key Differences
Unique to Semax:
Unique to Epitalon:
Detailed Analysis
Epitalon and Semax are used for different purposes and have limited overlap in their applications.
Which Should You Choose?
Choose Epitalon for Sleep Quality. Choose Semax for Cognitive Performance.