Semax & Selank vs MGF (Mechano Growth Factor)
A detailed comparison to help you understand the differences and choose the right peptide for your research goals.
Semax & Selank
A nootropic combination pairing two Russian-developed peptides for cognitive enhancement. Semax provides stimulating focus and neuroprotection while Selank offers anxiolytic and mood-stabilizing effects, creating a balanced cognitive enhancement stack.
Full details →MGF (Mechano Growth Factor)
MGF (Mechano Growth Factor) is a splice variant of IGF-1 that is produced locally in muscle tissue in response to mechanical stress. The non-PEGylated form has a very short half-life.
Full details →Side-by-Side Comparison
| Aspect | Semax & Selank | MGF (Mechano Growth Factor) |
|---|---|---|
| Mechanism | Semax enhances BDNF expression and modulates dopamine and serotonin systems for improved focus, memory, and neuroprotection. Selank affects BDNF and GABA systems, providing anxiolytic effects and immune modulation. Together they support cognitive function while managing stress and anxiety. | Activates muscle satellite cells (stem cells) and promotes their proliferation without differentiation, priming them for fusion with existing muscle fibers during repair and growth. |
| Typical Dosage | Semax: 200-600mcg intranasally 2-3 times daily. Selank: 250-500mcg intranasally 2-3 times daily. Can be used together or alternated based on needs. | Due to extremely short half-life (minutes), typical protocols use 100-200mcg injected directly into target muscles immediately post-workout. |
| Administration | Primarily administered intranasally for rapid brain uptake. N-Acetyl versions (NA-Semax, NA-Selank) offer enhanced stability and potency. Can also be injected subcutaneously. | Intramuscular injection into trained muscles within minutes of workout completion. Must be used immediately after reconstitution due to instability. |
| Side Effects | Semax may cause mild irritability or hair shedding. Selank may cause mild fatigue or nasal irritation. Both are generally well-tolerated. | Injection site soreness, potential hypoglycemia, localized swelling. Short half-life limits systemic effects. |
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