Palmitoyl Tetrapeptide-7 vs BNP (B-type Natriuretic Peptide)

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Palmitoyl Tetrapeptide-7

Palmitoyl Tetrapeptide-7 is an anti-inflammatory peptide that reduces IL-6 secretion. Combined with Palmitoyl Tripeptide-1, it forms Matrixyl 3000, addressing both collagen production and inflammation.

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BNP (B-type Natriuretic Peptide)

BNP is a cardiac neurohormone released primarily by ventricles in response to volume/pressure overload. It's a major biomarker for heart failure and has therapeutic applications as nesiritide.

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Side-by-Side Comparison

AspectPalmitoyl Tetrapeptide-7BNP (B-type Natriuretic Peptide)
MechanismSuppresses interleukin-6 (IL-6) production, reducing inflammation that contributes to skin aging. The anti-inflammatory effect complements collagen-stimulating peptides.Similar to ANP - activates NPR-A receptors to produce vasodilation, natriuresis, and RAAS suppression. Released in response to ventricular wall stress.
Typical DosageTopical: Usually combined with Palmitoyl Tripeptide-1 at similar concentrations (2-4%) in the Matrixyl 3000 complex.Nesiritide (recombinant BNP): 2mcg/kg IV bolus followed by 0.01mcg/kg/min continuous infusion for acute decompensated heart failure.
AdministrationTopical application with other anti-aging actives. The palmitoyl group enhances delivery into the skin.Intravenous administration only. Used in acute care settings for heart failure. BNP levels also used diagnostically.
Side EffectsExcellent tolerability profile. Anti-inflammatory properties may actually soothe sensitive skin.Hypotension (common and dose-limiting), headache, nausea, and potential renal function worsening in some patients.
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Key Differences

Unique to Palmitoyl Tetrapeptide-7:

Unique to BNP (B-type Natriuretic Peptide):

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