NA-Semax Amidate vs MGF (Mechano Growth Factor)

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

NA-Semax Amidate

NA-Semax Amidate (N-Acetyl Semax Amidate) is a modified version of Semax with enhanced stability and potency. Also known as NASA, it provides stronger and longer-lasting nootropic effects than standard Semax.

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MGF (Mechano Growth Factor)

MGF (Mechano Growth Factor) is a splice variant of IGF-1 that is produced locally in muscle tissue in response to mechanical stress. The non-PEGylated form has a very short half-life.

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Side-by-Side Comparison

AspectNA-Semax AmidateMGF (Mechano Growth Factor)
MechanismMaintains Semax's core actions on BDNF, NGF, and monoamine systems with improved pharmacokinetics. The modifications enhance CNS penetration and extend duration of action.Activates muscle satellite cells (stem cells) and promotes their proliferation without differentiation, priming them for fusion with existing muscle fibers during repair and growth.
Typical DosageIntranasal: 100-600mcg 1-2 times daily. Start with lower doses as it's more potent than standard Semax.Due to extremely short half-life (minutes), typical protocols use 100-200mcg injected directly into target muscles immediately post-workout.
AdministrationIntranasal spray is most common. Can be used sublingually. More stable than standard Semax in solution.Intramuscular injection into trained muscles within minutes of workout completion. Must be used immediately after reconstitution due to instability.
Side EffectsMay cause irritability, hair shedding (rare), or overstimulation at high doses. Generally well-tolerated.Injection site soreness, potential hypoglycemia, localized swelling. Short half-life limits systemic effects.
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Key Differences

Unique to NA-Semax Amidate:

Unique to MGF (Mechano Growth Factor):

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