Leuphasyl vs Epigen
A detailed comparison to help you understand the differences and choose the right peptide for your research goals.
Leuphasyl
Leuphasyl (Pentapeptide-18) is a cosmetic peptide that reduces muscle tension through a mechanism similar to enkephalins. Often combined with Syn-Ake for enhanced anti-wrinkle effects.
Full details →Epigen
Epigen is a member of the epidermal growth factor (EGF) family. It plays roles in skin regeneration and has been studied for wound healing and anti-aging applications.
Full details →Side-by-Side Comparison
| Aspect | Leuphasyl | Epigen |
|---|---|---|
| Mechanism | Mimics enkephalin and binds to enkephalin receptors on muscle cells, reducing acetylcholine release and thereby decreasing muscle contraction intensity. | Binds to and activates the EGF receptor (EGFR), promoting cell proliferation, migration, and differentiation. Involved in skin homeostasis and repair processes. |
| Typical Dosage | Topical: 3-8% concentration in serums. Often used in combination products with other muscle-relaxing peptides. | Topical: Typically used at low concentrations (ppm to low %) in cosmetic formulations. Research applications vary. |
| Administration | Topical application to expression lines. Best results with consistent twice-daily use over 8+ weeks. | Primarily topical application for skincare. Research may use other routes for systemic effects. |
| Side Effects | Very well-tolerated topically. No significant adverse effects reported at cosmetic concentrations. | Topical use generally well-tolerated. Theoretical concerns about promoting cell proliferation. |
| Best For |
What They Have in Common
Both Leuphasyl and Epigen are commonly used for: