Kisspeptin-10 vs Adamax

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Kisspeptin-10

Kisspeptin-10 is the active fragment of kisspeptin, a hormone that plays a crucial role in initiating puberty and regulating reproductive function. It acts upstream of GnRH in the hypothalamic-pituitary-gonadal axis.

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Adamax

Adamax is a modified version of Semax with an adamantane group attached, designed to enhance its nootropic effects and extend duration of action compared to standard Semax.

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Side-by-Side Comparison

AspectKisspeptin-10Adamax
MechanismBinds to KISS1R receptors in the hypothalamus, stimulating GnRH neurons to release GnRH. This triggers the downstream cascade of LH, FSH, and sex hormone production.Similar to Semax - enhances BDNF expression and modulates dopamine/serotonin systems. The adamantane modification may increase lipophilicity and CNS penetration.
Typical DosageResearch protocols vary widely. Studies have used IV boluses of 1-10mcg/kg or subcutaneous administration. Clinical applications still being developed.Intranasal: 100-500mcg 1-2 times daily. Lower doses than standard Semax may be effective due to enhanced potency.
AdministrationIV or subcutaneous injection. Has very short half-life requiring frequent administration or continuous infusion for sustained effects.Intranasal spray is most common route. More stable than standard Semax. Often used for acute cognitive enhancement.
Side EffectsLimited data. May cause flushing, increased heart rate, and changes in libido. Generally well-tolerated in studies.Similar to Semax - possible irritability, hair shedding, or overstimulation. May have stronger effects than standard Semax.
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Key Differences

Unique to Kisspeptin-10:

Unique to Adamax:

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