Ipamorelin vs Oxytocin

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Ipamorelin

Ipamorelin is a selective growth hormone secretagogue that stimulates the release of growth hormone from the pituitary gland without significantly affecting cortisol or prolactin.

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Oxytocin

Oxytocin is a natural hormone produced in the hypothalamus, often called the 'love hormone' or 'bonding hormone.' It plays key roles in social bonding, childbirth, lactation, and stress regulation.

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Side-by-Side Comparison

AspectIpamorelinOxytocin
MechanismActs as a ghrelin mimetic, binding to the ghrelin receptor (GHS-R) in the pituitary to stimulate GH release. Highly selective with minimal effect on other hormones.Binds to oxytocin receptors in the brain and peripheral tissues. Promotes social bonding, reduces anxiety and stress response, and has various peripheral effects on smooth muscle contraction.
Typical DosageTypical dosing ranges from 200-300mcg administered 2-3 times daily, often combined with CJC-1295.Intranasal: 20-40 IU (international units) for social/anxiolytic effects. Clinical uses (labor induction) require IV administration under medical supervision.
AdministrationSubcutaneous injection. Best results when administered fasted or before sleep. Often stacked with GHRH peptides.Intranasal spray for behavioral effects. IV only in clinical settings. Sublingual also possible. Best used situationally rather than continuously.
Side EffectsGenerally well-tolerated. May cause mild headaches, lightheadedness, or increased hunger initially.Intranasal: headache, nasal irritation, drowsiness. May cause over-attachment or emotional sensitivity. IV (clinical): uterine hyperstimulation, water retention.
Best For

What They Have in Common

Both Ipamorelin and Oxytocin are commonly used for:

Key Differences

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