Ipamorelin vs NA-Semax Amidate

A detailed comparison to help you understand the differences and choose the right peptide for your research goals.

Ipamorelin

Ipamorelin is a selective growth hormone secretagogue that stimulates the release of growth hormone from the pituitary gland without significantly affecting cortisol or prolactin.

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NA-Semax Amidate

NA-Semax Amidate (N-Acetyl Semax Amidate) is a modified version of Semax with enhanced stability and potency. Also known as NASA, it provides stronger and longer-lasting nootropic effects than standard Semax.

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Side-by-Side Comparison

AspectIpamorelinNA-Semax Amidate
MechanismActs as a ghrelin mimetic, binding to the ghrelin receptor (GHS-R) in the pituitary to stimulate GH release. Highly selective with minimal effect on other hormones.Maintains Semax's core actions on BDNF, NGF, and monoamine systems with improved pharmacokinetics. The modifications enhance CNS penetration and extend duration of action.
Typical DosageTypical dosing ranges from 200-300mcg administered 2-3 times daily, often combined with CJC-1295.Intranasal: 100-600mcg 1-2 times daily. Start with lower doses as it's more potent than standard Semax.
AdministrationSubcutaneous injection. Best results when administered fasted or before sleep. Often stacked with GHRH peptides.Intranasal spray is most common. Can be used sublingually. More stable than standard Semax in solution.
Side EffectsGenerally well-tolerated. May cause mild headaches, lightheadedness, or increased hunger initially.May cause irritability, hair shedding (rare), or overstimulation at high doses. Generally well-tolerated.
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Key Differences

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